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Phenotypes Associated with This Genotype
Genotype
MGI:3841176
Allelic
Composition		 Ftotm1Urt/Fto+
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ftotm1Urt mutation (0 available); any Fto mutation (76 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
growth/size/body
decreased susceptibility to diet-induced obesity ( J:147471 )
• mice have less weight gain and less body-fat percentage than controls after 12 weeks on a high-fat diet

homeostasis/metabolism
decreased susceptibility to diet-induced obesity ( J:147471 )
• mice have less weight gain and less body-fat percentage than controls after 12 weeks on a high-fat diet

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory