Phenotypes Associated with This Genotype

Genotype
MGI:3841035

• Allelic Composition: Pax2^1Neu/Pax2^1Neu
• Genetic Background: involves: 102

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality, complete penetrance ( J:89465 )

• rapid

endocrine/exocrine glands

endocrine/exocrine gland phenotype ( J:77446 )

N • unlike in zebrafish, thyroid development is normal

increased pancreatic beta cell mass ( J:89465 )

• the volume islet cells occupy in the pancreas is increased 3-fold compared to in wild-type mice

• islet cell size is increased 2.1-fold compared to in wild-type mice

increased pancreatic islet number ( J:89465 )

pancreatic islet hyperplasia ( J:89465 )