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Phenotypes Associated with This Genotype
Genotype
MGI:3840959
Allelic
Composition
Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy/Gt(ROSA)26Sor+
Sox9tm3(cre)Crm/Sox9+
Tg(tetO-Vegfa)1Kesh/0
Genetic
Background
involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(rtTA,EGFP)Nagy mutation (5 available); any Gt(ROSA)26Sor mutation (1084 available)
Sox9tm3(cre)Crm mutation (1 available); any Sox9 mutation (33 available)
Tg(tetO-Vegfa)1Kesh mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• the vascular network of the limbs is denser and more complex
• metacarpal centers are enriched for thicker vessels originating from the axial artery
• metacarpal centers are wider and split into a denser and more complex network of small capillaries in the interdigital areas
• however, formation of avascular areas is not affected


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
01/28/2026
MGI 6.24
The Jackson Laboratory