Phenotypes Associated with This Genotype

Genotype
MGI:3840817

• Allelic Composition: Ds/Ds⁺
• Genetic Background: involves: 129T1/Sv * DA/Hu * DBA/1J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

decreased survivor rate ( J:13012 )

perinatal lethality, incomplete penetrance ( J:13012 )

• the most severe abnormalities are lethal

embryo

abnormal embryo development ( J:13012 )

mirror image duplication ( J:13012 )

• duplicated limbs are common

abnormal embryonic tissue morphology ( J:13012 )

• a mix of abnormalities is seen that varies in number and type from mouse to mouse

neoplasm

increased skin hamartoma incidence ( J:13012 )

craniofacial

cranioschisis ( J:13012 )

skeleton

cranioschisis ( J:13012 )

scoliosis ( J:13012 )

• in sacral and caudal locations

limbs/digits/tail

polydactyly ( J:13012 )

integument

increased skin hamartoma incidence ( J:13012 )