Phenotypes for Trp53 Trp53bp2 MGI:3839867 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Trp53^tm1Brd/Trp53⁺ Trp53bp2^tm1Cdlo/Trp53bp2⁺
Genetic Background	involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Trp53bp2^tm1Cdlo mutation (0 available); any Trp53bp2 mutation (52 available)
Trp53^tm1Brd mutation (5 available); any Trp53 mutation (232 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

neoplasm

increased tumor incidence ( J:146764 )

• increased tumor incidence compared to wild-type controls but not compared to mice heterozygous for the Trp53 allele alone

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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