neoplasm
• increased tumor incidence but the spectrum of tumor types is similar to controls
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• unlike wild-type controls, mice develop tumors following exposure to 6.0 Gy or 10.5 Gy of gamma-radiation
• induced tumors are high grade lymphomas
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immune system
• attenuated T cell apoptotic response following gamma-irradiation
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cellular
• attenuated G0/G1 checkpoint function following gamma-irradiation
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hematopoietic system
• attenuated T cell apoptotic response following gamma-irradiation
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