Phenotypes Associated with This Genotype

Genotype
MGI:3839788

• Allelic Composition: Cdkn1b^tm1Ako/Cdkn1b^tm1Ako; Men1^tm1.1Ctre/Men1⁺
• Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

increased tumor incidence ( J:120835 )

• mice develop tumors of the pituitary, thyroid, parathyroid, pancreas, adrenal and testis

increased adrenal gland tumor incidence ( J:120835 )

increased pituitary gland tumor incidence ( J:120835 )

increased parathyroid gland tumor incidence ( J:120835 )

increased thyroid tumor incidence ( J:120835 )

increased pancreas tumor incidence ( J:120835 )

increased testis tumor incidence ( J:120835 )

♂

increased lung adenoma incidence ( J:120835 )

• in 6 % of mice

endocrine/exocrine glands

increased adrenal gland tumor incidence ( J:120835 )

increased pituitary gland tumor incidence ( J:120835 )

increased parathyroid gland tumor incidence ( J:120835 )

increased thyroid tumor incidence ( J:120835 )

increased pancreas tumor incidence ( J:120835 )

increased testis tumor incidence ( J:120835 )

♂

reproductive system

increased testis tumor incidence ( J:120835 )

♂

nervous system

increased pituitary gland tumor incidence ( J:120835 )

respiratory system

increased lung adenoma incidence ( J:120835 )

• in 6 % of mice