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Phenotypes Associated with This Genotype
Genotype
MGI:3837449
Allelic
Composition		 Becn1tm1Blev/Becn1+
Tg(CAG-EGFP/Map1lc3b)53Nmz/0
Genetic
Background		 involves: 129X1/SvJ * C57BL/6J * C57BL/6NCrj
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Becn1tm1Blev mutation (1 available); any Becn1 mutation (36 available)
Tg(CAG-EGFP/Map1lc3b)53Nmz mutation (5 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
impaired autophagy ( J:86953 )
• mutants show decreased autophagy during starvation conditions in muscle and bronchial epithelial cells

homeostasis/metabolism
impaired autophagy ( J:86953 )
• mutants show decreased autophagy during starvation conditions in muscle and bronchial epithelial cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory