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Phenotypes Associated with This Genotype
Genotype
MGI:3836912
Allelic
Composition		 Hoxa3tm3Mrc/Hoxa3tm3Mrc
Hoxb3tm1Mrc/Hoxb3tm1Mrc
Genetic
Background		 involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hoxa3tm3Mrc mutation (0 available); any Hoxa3 mutation (24 available)
Hoxb3tm1Mrc mutation (0 available); any Hoxb3 mutation (15 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal somatic motor system morphology ( J:86041 )
• incomplete loss of somatic motor neurons restricted to r5
• possibly involving a "change of fate" to V2 interneurons

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory