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Phenotypes Associated with This Genotype
Genotype
MGI:3836730
Allelic
Composition		 Bxs6BXSB/MpJ/Bxs6BXSB/MpJ
X/Yaa
Genetic
Background		 B10.BXSB-(D13Mit3-D13Mit78) Yaa
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bxs6BXSB/MpJ mutation (0 available); any Bxs6 mutation (0 available)
Yaa mutation (23 available); any Yaa mutation (27 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
autoimmune response ( J:145049 )
• increased levels of gp70 immune complex formation
increased autoantibody level ( J:145049 )
• increased gp70 autoantibody titers
glomerulonephritis ( J:145049 )
• increased glomerulonephritis incidence and severity
• decreased survival

hematopoietic system

renal/urinary system
glomerulonephritis ( J:145049 )
• increased glomerulonephritis incidence and severity
• decreased survival

growth/size/body
enlarged spleen ( J:145049 )

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory