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Phenotypes Associated with This Genotype
Genotype
MGI:3836580
Allelic
Composition
Nfatc4tm1Jmk/Nfatc4tm1Jmk
Tg(Myh6-Ppp3ca)37Eno/?
Genetic
Background
involves: 129S7/SvEvBrd * C57BL/6 * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nfatc4tm1Jmk mutation (1 available); any Nfatc4 mutation (38 available)
Tg(Myh6-Ppp3ca)37Eno mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• myofibrillar hypertrophy
• identical to control mice with the transgene alone
• three fold increase in heart/body weight ratio
• wall thickening

muscle
• myofibrillar hypertrophy

growth/size/body
• identical to control mice with the transgene alone
• three fold increase in heart/body weight ratio
• wall thickening


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory