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Phenotypes Associated with This Genotype
Genotype
MGI:3836576
Allelic
Composition		 Nfatc4tm1Jmk/Nfatc4tm1Jmk
Genetic
Background		 involves: 129S7/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nfatc4tm1Jmk mutation (1 available); any Nfatc4 mutation (38 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
cardiovascular system phenotype ( J:84138 )
N
• normal ventricular trabeculation
• normal thickening of compact zone
cardiac hypertrophy ( J:79608 )
• response to abdominal aortic constriction or continuous infusion of angiotensin II identical to controls
• increased heart weight/tibia length ratio when treated as above

growth/size/body
cardiac hypertrophy ( J:79608 )
• response to abdominal aortic constriction or continuous infusion of angiotensin II identical to controls
• increased heart weight/tibia length ratio when treated as above

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory