Phenotypes Associated with This Genotype

Genotype
MGI:3836406

• Allelic Composition: C2cd3^hty/C2cd3^{Gt(AG0177)Wtsi}
• Genetic Background: involves: 129P2/OlaHsd * C3H/He * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:142506 )

• disrupt embryonic development and caused embryonic lethality between E10.5 and E13.5

• overall phenotype is similar to homozygous C2cd3^hty

embryo

abnormal rostral-caudal body axis extension ( J:142506 )

• twisted body axis

cardiovascular system

pericardial edema ( J:142506 )

homeostasis/metabolism

pericardial edema ( J:142506 )