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Phenotypes Associated with This Genotype
Genotype
MGI:3835858
Allelic
Composition		 Gria2tm3Rsp/Gria2tm3Rsp
Tg(Slc6a3-icre)9075Gsc/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gria2tm3Rsp mutation (1 available); any Gria2 mutation (78 available)
Tg(Slc6a3-icre)9075Gsc mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal glutamate-mediated receptor currents ( J:139693 )
• the ratio of AMPA/NMDA-mediated receptor currents in the ventral tegmental area is significantly reduced compared to controls

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory