Phenotypes Associated with This Genotype

Genotype
MGI:3835597

• Allelic Composition: Pofut1^cax/Pofut1^cax
• Genetic Background: involves: C57BL/6J * CAST/Ei

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Axial skeleton and somite abnormalities in Pofut1^cax/Pofut1^cax mice

limbs/digits/tail

short tail ( J:145608 )

• Background Sensitivity: on this mixed genetic background tail length varies from nearly normal to almost complete absence of the tail

kinked tail ( J:145608 )

• Background Sensitivity: on this mixed background homozygotes can have a normal or kinked tail

growth/size/body

decreased body length ( J:145608 )

• Background Sensitivity: on this mixed genetic background decreased body length shows variable expressivity ranging from almost normal body length to noticably shortened body axis

skeleton

abnormal vertebral column morphology ( J:145608 )

• Background Sensitivity: even externally normal homozygotes will have malformations of the vertebral column, with varying severity on this mixed genetic background