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Phenotypes Associated with This Genotype
Genotype
MGI:3835122
Allelic
Composition
Tg(HLA-A2/H2-K)1Scr/?
Genetic
Background
involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(HLA-A2/H2-K)1Scr mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• infection with measles virus (MV) generates a large cytotoxic T cell population that can target human cells presenting MV antigens in the context of HLA-A2

hematopoietic system
• infection with measles virus (MV) generates a large cytotoxic T cell population that can target human cells presenting MV antigens in the context of HLA-A2


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory