Phenotypes for Brca1 Tg(Lck-cre)548Jxm Tg(TcrLCMV)327Sdz MGI:3834733 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Brca1^tm2Mak/Brca1^tm2Mak Tg(Lck-cre)548Jxm/? Tg(TcrLCMV)327Sdz/?
Genetic Background	involves: 129P2/OlaHsd * C57BL/6 * CBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Brca1^tm2Mak mutation (1 available); any Brca1 mutation (113 available)
Tg(Lck-cre)548Jxm mutation (2 available)
Tg(TcrLCMV)327Sdz mutation (11 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

decreased T cell proliferation ( J:63282 )

abnormal T cell number ( J:63282 )

decreased thymocyte number ( J:63282 )

increased double-negative T cell number ( J:63282 )

decreased double-positive T cell number ( J:63282 )

hematopoietic system

decreased T cell proliferation ( J:63282 )

abnormal T cell number ( J:63282 )

decreased thymocyte number ( J:63282 )

increased double-negative T cell number ( J:63282 )

decreased double-positive T cell number ( J:63282 )

endocrine/exocrine glands

decreased thymocyte number ( J:63282 )

cellular

decreased T cell proliferation ( J:63282 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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