About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3833618
Allelic
Composition		 Cdk6tm1Phin/Cdk6tm1Phin
Tg(Lck-Akt1*E40K)E-3Pnt/0
Genetic
Background		 involves: 129S4/SvJae
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cdk6tm1Phin mutation (0 available); any Cdk6 mutation (38 available)
Tg(Lck-Akt1*E40K)E-3Pnt mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
neoplasm ( J:144975 )
N
• unlike mice with only Tg(Lck-Akt1*E40K)E-3Pnt, no thymic lymphomas develop

immune system
abnormal T cell differentiation ( J:144975 )
• the majority of DN thymocytes are DN3 unlike in wild-type mice

hematopoietic system
abnormal T cell differentiation ( J:144975 )
• the majority of DN thymocytes are DN3 unlike in wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory