Phenotypes Associated with This Genotype

Genotype
MGI:3833562

• Allelic Composition: Ctnnb1^tm2Kem/Ctnnb1^tm2Kem; Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/0
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6J * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal retina vasculature morphology ( J:144980 )

• following treatment with tamoxifen, retinal vascular density is reduced compared to in wild-type retina

• however, endothelial junctional assemblies are normal

abnormal vascular regression ( J:144980 )

• excessive in the retina following tamoxifen treatment

vision/eye

abnormal retina vasculature morphology ( J:144980 )

• following treatment with tamoxifen, retinal vascular density is reduced compared to in wild-type retina

• however, endothelial junctional assemblies are normal

cellular

abnormal vascular regression ( J:144980 )

• excessive in the retina following tamoxifen treatment