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Phenotypes Associated with This Genotype
Genotype
MGI:3833108
Allelic
Composition
Tg(SOD1*H46R*H48Q)58Dbo/0
Genetic
Background
involves: C3H/HeJ * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• astrogliosis is observed in the cortical and hippocampal brain regions, the ventral midbrain, brain stem and spinal cord unlike in wild-type mice
• in the spinal cord of paralyzed mice

behavior/neurological
• at 4 to 6 months of age

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
amyotrophic lateral sclerosis type 1 DOID:0060193 OMIM:105400
J:119631


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/21/2017
MGI 6.08
The Jackson Laboratory