Analysis Tools
immune system
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• DSS-induced colitis is less severe in these mice as demonstrated by reduced scores in the disease activity index and in histology scores
(J:144784)
• colons from DSS-treated mice had decreased edema formation, less epithelial cell damage and decreased leukocyte formation than in controls
(J:144784)
• the number of eosoniphils that infiltrate the colon after 6 days of DSS treatment is about half that of wild-type controls
(J:144784)
• colonic biopsies from mice treated with DSS produce less IL-5, CCL11 and CCL5 when cultured
(J:144784)
• mice are resistant to colitis induced by dextran sulfate sodium (DSS) administration to the drinking water
(J:144927)
• after DSS administration, mice have delayed development of diarrhea, less rectal bleeding, and less weight loss
(J:144927)
• there was less shortening of the colon after DSS administration than in controls
(J:144927)
• less mice die from DSS- induced colitis than controls with all mice alive after 10 days of DSS administration compared to only 20% of controls
(J:144927)
• histology reveals less epithelial erosion and decreased submucosal inflammation resulting from DSS administration
(J:144927)
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• the number of eosoniphils that infiltrate the colon after 6 days of DSS treatment is about half that of wild-type controls
• colonic biopsies from mice treated with DSS produce less IL-5 when cultured
• colonic biopsies from mice treated with DSS produce CCL11 and CCL5 when cultured
• mice in an inflammatory state from DSS-induced colitis are resistant to hyperglycemia from glucose challenged compared to wild-type mice in the DSS-colitis model
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• colonic biopsies from mice treated with DSS produce CCL11 and CCL5 when cultured
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• more IL-10 is secreted in culture by colon biopsy specimens collected from mice treated with DSS than in controls
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• colonic biopsies from mice treated with DSS produce less IL-5 when cultured
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• less IL-6 is secreted in culture by colon biopsy specimens collected from mice treated with DSS than in controls
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digestive/alimentary system
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• DSS-induced colitis is less severe in these mice as demonstrated by reduced scores in the disease activity index and in histology scores
(J:144784)
• colons from DSS-treated mice had decreased edema formation, less epithelial cell damage and decreased leukocyte formation than in controls
(J:144784)
• the number of eosoniphils that infiltrate the colon after 6 days of DSS treatment is about half that of wild-type controls
(J:144784)
• colonic biopsies from mice treated with DSS produce less IL-5, CCL11 and CCL5 when cultured
(J:144784)
• mice are resistant to colitis induced by dextran sulfate sodium (DSS) administration to the drinking water
(J:144927)
• after DSS administration, mice have delayed development of diarrhea, less rectal bleeding, and less weight loss
(J:144927)
• there was less shortening of the colon after DSS administration than in controls
(J:144927)
• less mice die from DSS- induced colitis than controls with all mice alive after 10 days of DSS administration compared to only 20% of controls
(J:144927)
• histology reveals less epithelial erosion and decreased submucosal inflammation resulting from DSS administration
(J:144927)
|
homeostasis/metabolism
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• leptin circulating levels in the sera of fasted mice is almost two-thirds less than in controls
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• mice in an inflammatory state from DSS-induced colitis are resistant to hyperglycemia when challenged with glucose compared to controls
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hematopoietic system
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• the number of eosoniphils that infiltrate the colon after 6 days of DSS treatment is about half that of wild-type controls
• colonic biopsies from mice treated with DSS produce less IL-5 when cultured
• colonic biopsies from mice treated with DSS produce CCL11 and CCL5 when cultured
• mice in an inflammatory state from DSS-induced colitis are resistant to hyperglycemia from glucose challenged compared to wild-type mice in the DSS-colitis model
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