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Phenotypes Associated with This Genotype
Genotype
MGI:3832564
Allelic
Composition		 Lynmld4/Lynmld4
Mpltm1Wsa/Mpltm1Wsa
Genetic
Background		 B6.129S1-Mpltm1Wsa
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lynmld4 mutation (1 available); any Lyn mutation (66 available)
Mpltm1Wsa mutation (1 available); any Mpl mutation (48 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased leukocyte cell number ( J:144799 )
• WBC is reduced by more than a third compared to Mpltm1Wsa homozygote controls

hematopoietic system
decreased erythrocyte cell number ( J:144799 )
• there is a slight reduction in the number of red blood cells compared to Mpltm1Wsa homozygote controls
thrombocytopenia ( J:144799 )
• platelet count is reduced by about half compared to Mpltm1Wsa homozygote controls
decreased leukocyte cell number ( J:144799 )
• WBC is reduced by more than a third compared to Mpltm1Wsa homozygote controls

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory