Mouse Genome Informatics
cn
    Ldb3tm4Chen/Ldb3tm4Chen
Tg(Myh6-cre/Esr1*)1Jmk/0

involves: 129S1/Sv * 129X1/SvJ * Black Swiss * FVB/N
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
mortality/aging
• all mice die between 1 and 16 weeks after tamoxifen treatment

cardiovascular system
• after tamoxifen treatment
• both ventricles are severely dilated after tamoxifen treatment
• both ventricles are severely dilated after tamoxifen treatment
• decreased heart function one month after tamoxifen treatment
• after tamoxifen treatment

muscle
• after tamoxifen treatment

Mouse Models of Human Disease
OMIM IDRef(s)
Cardiomyopathy, Dilated, 1C; CMD1C 601493 J:144739