Phenotypes Associated with This Genotype

Genotype
MGI:3831728

• Allelic Composition: Ts(16C-tel)1Cje/0
• Genetic Background: involves: C3H/HeSnJ * C57BL/6J * CD-1 * Rb(16.17)32Lub * STOCK Rb(11.16)2H/H

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal spatial learning ( J:47907 )

• in a hidden platform test and reverse platform test of a Morris water maze, mice exhibit impaired performance compared to wild-type mice

• learning over a 3 month period in the Morris water maze tests improves but remains impaired compared to in wild-type mice

nervous system

nervous system phenotype ( J:47907 )

N • adult brain gross morphology is normal

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
Down syndrome		DOID:14250	OMIM:190685	J:47907