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Phenotypes Associated with This Genotype
Genotype
MGI:3830054
Allelic
Composition		 Il17ftm1Yiw/Il17ftm1Yiw
Il1rntm1Yiw/Il1rntm1Yiw
Genetic
Background		 involves: 129 * BALB/c
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il17ftm1Yiw mutation (0 available); any Il17f mutation (26 available)
Il1rntm1Yiw mutation (0 available); any Il1rn mutation (22 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
rheumatoid arthritis ( J:143719 )
• mice develop autoimmune arthritis of the joints though with about 20% less incidence than in mice homozygote for just the Il1rntm1Yiw allele

skeleton
rheumatoid arthritis ( J:143719 )
• mice develop autoimmune arthritis of the joints though with about 20% less incidence than in mice homozygote for just the Il1rntm1Yiw allele

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory