Phenotypes Associated with This Genotype

Genotype
MGI:3829248

• Allelic Composition: Tg(THY1-APOD1)1Era/0
• Genetic Background: B6.Cg-Tg(THY1-APOD1)1Era

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

decreased susceptibility to xenobiotic induced morbidity/mortality ( J:143809 )

• following paraquat treatment median life span is increased compared to similarly treated wild type mice

behavior/neurological

increased vertical activity ( J:143809 )

homeostasis/metabolism

abnormal lipid homeostasis ( J:143809 )

• 2 weeks after treatment with paraquat (a reactive oxygen species generator) lipid peroxidation is not significantly elevated compared to untreated controls unlike in similarly treated wild type mice

decreased susceptibility to xenobiotic induced morbidity/mortality ( J:143809 )

• following paraquat treatment median life span is increased compared to similarly treated wild type mice