About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3828048
Allelic
Composition
Npr2cn/Npr2cn
Genetic
Background
involves: AKR/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Npr2cn mutation (2 available); any Npr2 mutation (9 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• a small percentage of sensory axons extend directly towards the central canal unlike in wild-type mice
• the dorsal funiculus is reduced in size compared to in wild-type mice

skeleton
• growth of femora and tibiae is sub-normal in pre-wean homozygotes and growth is severely interupted at weaning, between 21 and 28 days of age, before resuming slow growth

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
achondroplasia DOID:4480 OMIM:100800
J:26341


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
10/08/2019
MGI 6.14
The Jackson Laboratory