Phenotypes Associated with This Genotype

Genotype
MGI:3826997

• Allelic Composition: Zfp57^tm1.1Xjli/Zfp57^tm1.1Xjli
• Genetic Background: either: 129S6/SvEvTac-Zfp57^tm1.1Xjli or (involves: 129S6/SvEvTac * Black Swiss * FVB/N)

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

lethality throughout fetal growth and development, incomplete penetrance ( J:143283 )

• 80% of homozygous mice from homozygous females die between E14.5 and E16.5

postnatal lethality, incomplete penetrance ( J:143283 )

• half as many mice as expected are alive at weaning

• no homozygous mice from homozygous females survive to weaning

cellular

abnormal imprinting ( J:143283 )

• in homozygous mutant embryos derived from a null females

maternal effect ( J:143283 )

• 80% of homozygous mice from homozygous females die between E14.5 and E16.5

• no homozygous mice from homozygous females survive to weaning

• imprinting is abnormal in homozygous mutant embryos derived from a null females