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Phenotypes Associated with This Genotype
Genotype
MGI:3826855
Allelic
Composition
F3tm1Nmk/F3tm1Nmk
Myl2tm1(cre)Krc/?
Genetic
Background
involves: 129S4/SvJae * 129S6/SvEvTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
F3tm1Nmk mutation (1 available); any F3 mutation (26 available)
Myl2tm1(cre)Krc mutation (2 available); any Myl2 mutation (20 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• normal hearts at 6 months
• hemosiderin deposition and fibrosis in 3 of 12 hearts examined at 9 months
• isoproterenol treatment of 3 month old mice also results in hemosiderin deposition and fibrosis


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory