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Phenotypes Associated with This Genotype
Genotype
MGI:3826833
Allelic
Composition		 Rag1tm1Mom/Rag1tm1Mom
Tyrp1B-w/Tyrp1B-w
X/Tg(Tcra,Tcrb)9Rest
Genetic
Background		 involves: 101/Rl * 129S7/SvEvBrd * C3H/Rl * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rag1tm1Mom mutation (49 available); any Rag1 mutation (120 available)
Tg(Tcra,Tcrb)9Rest mutation (1 available)
Tyrp1B-w mutation (14 available); any Tyrp1 mutation (162 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
abnormal tumor susceptibility ( J:138466 )
• inoculation with B16 melanoma cells results in 100% tumor take in transgenic mice; tumor growth is only minimally delayed compared to non-transgenic control mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory