About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3826463
Allelic
Composition		 Rhohtm1Brak/Rhohtm1Brak
Tg(TcraTcrb)425Cbn/?
Genetic
Background		 involves: 129/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rhohtm1Brak mutation (0 available); any Rhoh mutation (11 available)
Tg(TcraTcrb)425Cbn mutation (6 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:143161 )
N
• no increase in DN4 cells observed
decreased CD4-positive, alpha-beta T cell number ( J:143161 )
• severely impaired generation of CD4+ cells

hematopoietic system
decreased CD4-positive, alpha-beta T cell number ( J:143161 )
• severely impaired generation of CD4+ cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory