Phenotypes Associated with This Genotype

Genotype
MGI:3823254

• Allelic Composition: Efnb3^tm1Nwg/Efnb3^tm1Nwg
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

abnormal gait ( J:82479 )

• rabbit like gait

nervous system

abnormal motor neuron innervation pattern ( J:82479 )

• corticospinal tract nerve fibers aberrantly cross the spinal cord midline to the contralateral side

abnormal corticospinal tract morphology ( J:82479 )

• corticospinal tract nerve fibers aberrantly cross the spinal cord midline to the contralateral side

abnormal central pattern generator function ( J:82479 )

• lumbar segments of the spinal cords of neonates exhibit synchronous left-right ventral root activity instead of the left-right alternating activity observed in wild-type after NMDA and serotonin application