Phenotypes for Gli3 MGI:3823094 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Gli3^add/Gli3^Xt
Genetic Background	involves: 101/H * C3H/HeH * C57BL/6 * CBA/H * SJL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gli3^add mutation (0 available); any Gli3 mutation (84 available)
Gli3^Xt mutation (1 available); any Gli3 mutation (84 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

limbs/digits/tail

polydactyly ( J:11318 )

• on 50% of animals, seven digits are observed on fore- and hindlimbs

• when double mutants are backcrossed to wild-type (C57BL/6 x SJL)F1 animals, 50% of mice display only 1 extra toe per hindlimb

abnormal digit development ( J:11318 )

• in some animals 2 of the extra digits are fused

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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