Phenotypes Associated with This Genotype

Genotype
MGI:3822764

• Allelic Composition: \Hesx1^tm1(cre)Jpmb/\Hesx1^tm1(cre)Jpmb
• Genetic Background: B6.129S-Hesx1^tm1(cre)Jpmb

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

perinatal lethality, complete penetrance ( J:135132 )

• no homozygous offspring are identified

nervous system

abnormal telencephalon development ( J:135132 )

• mice show reduced or absent telencephalon at 12.5 dpc (days post coitum)

vision/eye

abnormal eye development ( J:135132 )

• eye defects are fully penetrant with variable expressivity

microphthalmia ( J:135132 )

• some embryos display unilateral microphthalmia

anophthalmia ( J:135132 )

• some embryos display bilateral anophthalmia