Phenotypes Associated with This Genotype

Genotype
MGI:3822534

• Allelic Composition: Trp73^tm1Mak/Trp73⁺
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

neoplasm

increased lymphoma incidence ( J:142848 )

• 10% of mice develop lymphoma that infiltrate more than one organ compared to 6% of wild-type mice that develop non-infiltrating lymphoma

increased T cell derived lymphoma incidence ( J:142848 )

• 5% of mice develop thymic lymphoma

increased carcinoma incidence ( J:142848 )

• 5% of mice develop colon carcinoma in situ

increased lung adenocarcinoma incidence ( J:142848 )

• 5% of mice develop lung adenocarcinoma

increased hemangiosarcoma incidence ( J:142848 )

• in 5% of mice

endocrine/exocrine glands

increased T cell derived lymphoma incidence ( J:142848 )

• 5% of mice develop thymic lymphoma

respiratory system

increased lung adenocarcinoma incidence ( J:142848 )

• 5% of mice develop lung adenocarcinoma

hematopoietic system

increased T cell derived lymphoma incidence ( J:142848 )

• 5% of mice develop thymic lymphoma

immune system

increased T cell derived lymphoma incidence ( J:142848 )

• 5% of mice develop thymic lymphoma