Analysis Tools
homeostasis/metabolism
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• total plasma cholesterol levels (TPC) are 132 +/- 12 mg/dl compared to normal range of control mice (70-100 mg/dl); levels of transgenic Apoe-null mice are almost normalized to levels of control littermates heterozygous for the mouse Apoe allele
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• mice have >3% (about 2.2 ug/ml) of wild-type plasma Apoe levels
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cardiovascular system
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• mice show almost complete suppression of cholesteryl ester deposition (CE lesions) compared to nontransgenic Apoe-null littermates
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