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Phenotypes Associated with This Genotype
Genotype
MGI:3822322
Allelic
Composition		 Rb1tm1Tyj/Rb1+
Tg(S100b-v-erbB)4496Waw/0
Genetic
Background		 involves: 129S2/SvPas * C57BL/6J * DBA/2J * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rb1tm1Tyj mutation (4 available); any Rb1 mutation (116 available)
Tg(S100b-v-erbB)4496Waw mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
increased glioma incidence ( J:82649 )
• mice develop gliomas in the same pattern and with the same pathology as in Tg(S100b-v-erbB)4496Waw mice

nervous system
increased glioma incidence ( J:82649 )
• mice develop gliomas in the same pattern and with the same pathology as in Tg(S100b-v-erbB)4496Waw mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/13/2026
MGI 6.24 		The Jackson Laboratory