Phenotypes Associated with This Genotype

Genotype
MGI:3822313

• Allelic Composition: Reln^rl-8J/Reln^rl-8J
• Genetic Background: STOCK Reln^rl-8J/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:142871 )

behavior/neurological

abnormal motor capabilities/coordination/movement ( J:142871 )

impaired righting response ( J:142871 )

ataxia ( J:142871 )

abnormal gait ( J:142871 )

nervous system

abnormal hippocampus morphology ( J:142871 )

• neurons of the hippocampal gyrus are scattered in irregular wavy layers

abnormal dentate gyrus morphology ( J:142871 )

abnormal cerebral cortex morphology ( J:142871 )

• scrambled layering in the cortex

abnormal cerebellar cortex morphology ( J:142871 )

• cerebellum is small with scrambled Purkinje and granule cells

small cerebellum ( J:142871 )