Phenotypes Associated with This Genotype

Genotype
MGI:3821885

• Allelic Composition: Tg(CAG-cre/Esr1*)5Amc/0; Tg(CAG-LacZ,-ACVR1*,-EGFP)35-1Mis/0
• Genetic Background: involves: C57BL/6 * CBA * DBA/2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

skeleton phenotype ( J:142253 )

N • unlike mice treated with adenoviral cre, tamoxifen treated mice exhibit normal ossification and joint mobility

abnormal skeleton morphology ( J:142253 )

• tamoxifen treated mice injected with a control adenovirus exhibit decreased limb motion and small ectopic calcifications by P14

muscle

muscle phenotype ( J:142253 )

N • unlike mice treated with adenoviral cre, tamoxifen treated mice exhibit normal myocytes