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Phenotypes Associated with This Genotype
Genotype
MGI:3820420
Allelic
Composition		 Nrxn2tm3Sud/Nrxn2tm3Sud
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nrxn2tm3Sud mutation (0 available); any Nrxn2 mutation (87 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging

growth/size/body
decreased body weight ( J:142107 )
• surviving mice display a 30-40% decrease in body weight compared to controls

nervous system
abnormal inhibitory postsynaptic currents ( J:142107 )
• in cortical slices IPSCs are decreased

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory