Phenotypes Associated with This Genotype

Genotype
MGI:3820209

• Allelic Composition: Igf2r^tm1Arge/Igf2r⁺
• Genetic Background: involves: 129/Sv * C57BL/6J * MF1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

decreased survivor rate ( J:34584 )

• Background Sensitivity: when this allele is inherited maternally, 0.7% of mice survive the postnatal period compared to 16.2% on an 129/Sv MF1 background

lethality throughout fetal growth and development, incomplete penetrance ( J:34584 )

• when this allele is inherited maternally, some mice die between E17.5 and E18.5

postnatal lethality, incomplete penetrance ( J:34584 )

• when this allele is inherited maternally, 0.7% of mice survive the postnatal period compared to 16.2% on an 129/Sv MF1 background