Phenotypes Associated with This Genotype

Genotype
MGI:3819773

• Allelic Composition: Uqcrfs1^tm1Ctm/Uqcrfs1^tm1Ctm
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

pigmentation

abnormal dorsoventral coat patterning ( J:141714 )

• around 4 to 7 months of age, mice develop dark patches in the dorsal brown coat

• with age these patches spread to fill almost all of the dorsal coat but the color of the ventral coat does not change

• patches eventually turn grey

• treatment with N-acetyl cysteine for 60 days failed to prevent the color change

integument

abnormal dorsoventral coat patterning ( J:141714 )

• around 4 to 7 months of age, mice develop dark patches in the dorsal brown coat

• with age these patches spread to fill almost all of the dorsal coat but the color of the ventral coat does not change

• patches eventually turn grey

• treatment with N-acetyl cysteine for 60 days failed to prevent the color change