Phenotypes Associated with This Genotype

Genotype
MGI:3819169

• Allelic Composition: Ret^tm1Giro/Ret⁺
• Genetic Background: 129.129P2-Ret^tm1Giro

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

adrenal cortical hyperplasia ( J:141658 )

• 14% to 15% of mice exhibit adrenal gland cortical nodular regeneration or hyperplasia

abnormal thyroid gland morphology ( J:141658 )

• thyroid gland dysplasia and adenoma are observed in 12% of mice unlike in wild-type mice

increased thyroid adenoma incidence ( J:141658 )

• thyroid gland dysplasia and adenoma are observed in 12% of mice unlike in wild-type mice

neoplasm

increased thyroid adenoma incidence ( J:141658 )

• thyroid gland dysplasia and adenoma are observed in 12% of mice unlike in wild-type mice