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Phenotypes Associated with This Genotype
Genotype
MGI:3818750
Allelic
Composition		 Rag1tm1Mom/Rag1tm1Mom
Xrcc5tm1Dbr/Xrcc5tm1Dbr
Genetic
Background		 involves: 129S7/SvEvBrd * C57BL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rag1tm1Mom mutation (56 available); any Rag1 mutation (132 available)
Xrcc5tm1Dbr mutation (0 available); any Xrcc5 mutation (71 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
increased cerebellar granule cell number ( J:141515 )
• mice exhibit a focal increase in external granule cells compared to in wild-type mice

neoplasm
neoplasm ( J:141515 )
N
• despite the increase in granule cells, mice do not develop medulloblastoma

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory