Phenotypes for Rag1 Xrcc5 MGI:3818750 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Rag1^tm1Mom/Rag1^tm1Mom Xrcc5^tm1Dbr/Xrcc5^tm1Dbr
Genetic Background	involves: 129S7/SvEvBrd * C57BL

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rag1^tm1Mom mutation (56 available); any Rag1 mutation (133 available)
Xrcc5^tm1Dbr mutation (0 available); any Xrcc5 mutation (72 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

increased cerebellar granule cell number ( J:141515 )

• mice exhibit a focal increase in external granule cells compared to in wild-type mice

neoplasm

neoplasm ( J:141515 )

N	• despite the increase in granule cells, mice do not develop medulloblastoma

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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