Phenotypes Associated with This Genotype

Genotype
MGI:3818682

• Allelic Composition: Rhcg^tm1Ibmm/Rhcg^tm1Ibmm
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

renal/urinary system

renal tubular acidosis ( J:141372 )

• mice show an impaired ability to excrete ammonium when drinking acidified water, barely reaching 25% of the wild-type response

growth/size/body

decreased body weight ( J:141372 )

• mice loss 20% of their body weight when given an acid load challenge in their drinking water compared to wild-type mice that do not loss weight

homeostasis/metabolism

renal tubular acidosis ( J:141372 )

• mice show an impaired ability to excrete ammonium when drinking acidified water, barely reaching 25% of the wild-type response