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Phenotypes Associated with This Genotype
Genotype
MGI:3818476
Allelic
Composition		 Zbtb7btm2Litt/Zbtb7btm2Litt
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Zbtb7btm2Litt mutation (2 available); any Zbtb7b mutation (26 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
absent CD4-positive, alpha-beta T cells ( J:141519 )
• CD4+ T cells are almost completely absent

immune system
absent CD4-positive, alpha-beta T cells ( J:141519 )
• CD4+ T cells are almost completely absent

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory