Phenotypes for Scn8a Scnm1 MGI:3818067 MGI Mouse

About Help FAQ

Phenotypes Associated with This Genotype

Allelic Composition	Scn8a^med-J/Scn8a^med-J Scnm1^tm1.1Mm/Scnm1^tm1.1Mm
Genetic Background	involves: C57BL/6 * FVB * SJL * STOCK Krt71^Ca

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Scn8a^med-J mutation (2 available); any Scn8a mutation (98 available)
Scnm1^tm1.1Mm mutation (0 available); any Scnm1 mutation (17 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

premature death ( J:141236 )

behavior/neurological

hindlimb paralysis ( J:141236 )

• in all mice

cellular

abnormal cell physiology ( J:141236 )

• mice exhibit reduced splicing of the Scn8a^med-J transcript compared to in wild-type mice and Scn8a^med-J Scnm1^s double homozygotes

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/25/2025 MGI 6.24