immune system
• female mice have substantial numbers of HY-specific CD4+ T cells while having a complete absence of HY-specific CD8+ T cells, which is a reversal of the T cell populations that normally develop in female mice carrying just the Tg(TcraH-Y,TcrbH-Y)71Vbo allele
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hematopoietic system
• female mice have substantial numbers of HY-specific CD4+ T cells while having a complete absence of HY-specific CD8+ T cells, which is a reversal of the T cell populations that normally develop in female mice carrying just the Tg(TcraH-Y,TcrbH-Y)71Vbo allele
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