Phenotypes for Lmna MGI:3817521 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Lmna^tm1Lgf/Lmna^tm1Stw
Genetic Background	involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lmna^tm1Lgf mutation (0 available); any Lmna mutation (84 available)
Lmna^tm1Stw mutation (3 available); any Lmna mutation (84 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

premature death ( J:113119 )

• mice die between 10 and 14 weeks of age

skeleton

abnormal skeleton morphology ( J:113119 )

• mice develop fractures in the extremities by 8 weeks of age

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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