About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3817442
Allelic
Composition		 Naip5tm1Vnce/Naip5tm1Vnce
Genetic
Background		 C57BL/6-Naip5tm1Vnce
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Naip5tm1Vnce mutation (0 available); any Naip5 mutation (103 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased interleukin-1 beta secretion ( J:141008 )
• macrophage fail to release Il1 beta after infection with Legionella pneumophila

cellular
decreased cell death ( J:141008 )
• macrophage fail to undergo pyroptotic cell death after infection with Legionella pneumophila

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory